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Generic Zofran is used for preventing nausea and vomiting due to cancer chemotherapy or surgery. It may also be used for other conditions.

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Also known as:  Ondansetron.

Description

Generic Zofran is used for preventing nausea and vomiting due to cancer chemotherapy or surgery. It may also be used for other conditions.

Generic Zofran is a serotonin 5-HT3 receptor blocker. It works by blocking a chemical thought to be a cause of nausea and vomiting in certain situations (e.g., chemotherapy).

Zofran is also known as Ondansetron, Vomiof, Danzetron, Ondaz.

Generic name of Generic Zofran is Ondansetron.

Brand name of Generic Zofran is Zofran.

Dosage

Take each dose with a full glass of water.

Take Generic Zofran with food or an antacid to lessen stomach discomfort.

If you want to achieve most effective results do not stop taking Generic Zofran suddenly.

Overdose

If you overdose Generic Zofran and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at temperature between 2 and 30 degrees C (36 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

Assessment of the emetogenic potential of intrathecal chemotherapy and response to prophylactic treatment with ondansetron. 5-HT3 receptor antagonism and psychoactivity. Combining ondansetron and naltrexone effectively treats biologically predisposed alcoholics: from hypotheses to preliminary clinical evidence. 5-Hydroxytryptamine-induced potentiation of cholinergic responses to electrical field stimulation in pig detrusor muscle. Buy zofran.

Contraindications

Do not take Generic Zofran if you are allergic to Generic Zofran components.

Be careful with Generic Zofran if you're pregnant or you plan to have a baby, or you are a nursing mother.

Generic Zofran should be used with extreme caution in children younger than 4 months old. Safety and effectiveness in these children have not been confirmed.

Avoid alcohol.

Do not stop taking Generic Zofran suddenly.

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Ondansetron plus dexamethasone compared to the 'standard' metoclopramide combination. A preliminary randomized, double-blind, placebo-controlled study of the safety and efficacy of ondansetron in the treatment of cocaine dependence. Biphasic emetic response of cyclophosphamide in the ferret. Relief of cholestatic pruritus by a novel class of drugs: 5-hydroxytryptamine type 3 (5-HT3) receptor antagonists: effectiveness of ondansetron.

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Enhanced gastric retention of solid resin beads as a marker for emetic potential of agents in rats. Ondansetron and Delta-9-tetrahydrocannabinol interfere with the establishment of lithium-induced conditioned taste avoidance in the house musk shrew (Suncus murinus). Pharmacological properties and functions of central 5-HT3 receptors. Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism.

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The effect on motion sickness and oculomotor function of GR 38032F, a 5-HT3-receptor antagonist with anti-emetic properties. The oral NK(1) antagonist, aprepitant, given with standard antiemetics provides protection against nausea and vomiting over multiple cycles of cisplatin-based chemotherapy: a combined analysis of two randomised, placebo-controlled phase III clinical trials. A within-group design of nontreatment seeking 5-HTTLPR genotyped alcohol-dependent subjects receiving ondansetron and sertraline. Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking.

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Mianserin, but not ondansetron, reduces the locomotor stimulating effect of ethanol in preweanling rats. Chemotherapy-induced emesis: management of early and delayed emesis in milder emetogenic regimens. Rifampin and rifabutin drug interactions: an update. Ondansetron combined with ST36 (Zusanli) acupuncture point injection for postoperative vomiting.

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Optimal control of cyclophosphamide-induced emesis. Chronotropic action of 5-hydroxytryptamine (5-HT) on colonic migrating motor complexes (CMMCs) in the isolated mouse colon. New drugs for the treatment of functional dyspepsia. Rapidfilm: an innovative pharmaceutical form designed to improve patient compliance.

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Topotecan in pediatric patients with recurrent and progressive solid tumors: a Pediatric Oncology Group phase II study. Acupressure using ondansetron versus metoclopramide on reduction of postoperative nausea and vomiting after strabismus surgery. A comparison of prophylactic ondansetron hydrochloride and droperidol for strabismus repair in adults. 5-HT3 receptor modulation of behavior during withdrawal from continuous or intermittent cocaine.

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A phase II study of ondansetron as antiemetic prophylaxis in patients receiving carboplatin for advanced ovarian cancer. The North Thames Ovary Group. Review of therapeutic agents for burns pruritus and protocols for management in adult and paediatric patients using the GRADE classification. Prevention by the 5-HT3 receptor antagonist, ondansetron, of morphine-dependence and tolerance in the rat. Palonosetron in prevention of nausea and vomiting after highly emetogenic chemotherapy before haematopoietic stem cell transplantation-single center experience.

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Granisetron: the second serotonin-receptor antagonist. Delayed Presentation of DPD Deficiency in Colorectal Cancer. Evidence of a role for descending serotonergic facilitation in a rat model of cancer-induced bone pain. A pharmacological analysis of receptors mediating the excitatory response to 5-hydroxytryptamine in the guinea-pig isolated trachea.

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Opioid-free total intravenous anesthesia with propofol, dexmedetomidine and lidocaine infusions for laparoscopic cholecystectomy: a prospective, randomized, double-blinded study. Nausea and emesis remain significant problems of chemotherapy despite prophylaxis with 5-hydroxytryptamine-3 antiemetics: a University of Rochester James P. Wilmot Cancer Center Community Clinical Oncology Program Study of 360 cancer patients treated in the community. Central action of 5-HT3 receptor ligands in the regulation of sleep-wakefulness and raphe neuronal activity in the rat. Intestinal obstruction in pregnancy by ondansetron.

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A randomized double-blind comparison of ondansetron and metoclopramide in the prophylaxis of emesis induced by cyclophosphamide, fluorouracil, and doxorubicin or epirubicin chemotherapy. Implications of anesthesia in children with long QT syndrome. Pharmacological characterization of 5-Hydroxytryptamine-receptor subtypes in circular muscle from the rat stomach. Aprepitant: drug-drug interactions in perspective.

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