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Paracetamol is a medication that is capable to relieve pain and acts like antipyretic that's why it is one of the most popular preparations used for treating cold and flu. Paracetamol is also used for the fast relief of headache, including migraine pain, dental pain, neuralgia, muscular and rheumatic pain, as well as algomenorrhea, pain caused be injurys and burns.

Other names for this medication:
Calpol, Aspirin, Anacin, Ben-u-ron, Biogesic, Crocin, Dafalgan, Dapa, Dolo, Datril, Efferalgan, DayQuil, Feverall, Fibi, Panadrex, Panamax, Parol, Paratabs, Phenaphen, Tylenol, Uphamol, Valorin

Similar Products:
Dolomol, Piaron

 

Also known as:  Paracetamol.

Description

Paracetamol is a antipyretic with pain relieving action that is widely applied for treating cold and flu. Paracetamol blocks the synthesis of prostaglandins in the central nervous system by inhibiting cyclooxygenase that has certain action on the pain centers and thermoregulation.

Paracetamol has no adverse effect on the salt-water metabollism in the human body and it doesn't affect gastrointestinal tract.

Dosage

The usual dose of paracetamol is 2 tablets. Swallow the tablets whole with a drink of water.

Overdose

If you overdose Paracetamol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

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Side effects

Biodegradation screening of chemicals in an artificial matrix simulating the water-sediment interface. Factors associated with physical activity in Australians with hip or knee osteoarthritis. Gait analysis in rats with single joint inflammation: influence of experimental factors. Assessing and treating pain in movement disorders, amyotrophic lateral sclerosis, severe acquired brain injury, disorders of consciousness, dementia, oncology and neuroinfectivology. Evidence and recommendations from the Italian Consensus Conference on Pain in Neurorehabilitation. A randomized trial examining preoperative sedative medication and postoperative sleep in children. Buy paracetamol. Antipyretic strategies for acute stroke: a nationwide survey among German stroke units.

Contraindications

Do not take Paracetamol if you are allergic to Paracetamol components.

Avoid using Paracetamol in case of followng conditions: liver failure, liver problems, serious kidney problems, shock, overdose of the drug acetaminophen, poor nutrition.

Avoid alcohol.

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Paracetamol (Acetaminophen) in stroke 2 (PAIS 2): protocol for a randomized, placebo-controlled, double-blind clinical trial to assess the effect of high-dose paracetamol on functional outcome in patients with acute stroke and a body temperature of 36.5 °C or above. INFULGAN-OPTIMAL ANALGETIC DRUG FOR USE IN LAPAROSCOPIC SURGERY. Use of aspirin, non-steroidal anti-inflammatory drugs, and acetaminophen (paracetamol), and risk of psoriasis and psoriatic arthritis: a cohort study. Self-poisoning: current trends and practice in a U.K. teaching hospital. Mechanism of action of pre-meal consumption of whey protein on glycemic control in young adults. Efficacy of pain treatment on mood syndrome in patients with dementia: a randomized clinical trial. Inhibition of biomass activity in the via nitrite nitrogen removal processes by veterinary pharmaceuticals.

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Five-year update on the occurrence of alcohol and other drugs in blood samples from drivers killed in road-traffic crashes in Sweden. Evaluation of multiday analgesia with etoricoxib in a double-blind, randomized controlled trial using the postoperative third-molar extraction dental pain model. Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats. The role of hepatitis E virus infection in adult Americans with acute liver failure. Hollow mesoporous TiO2 microspheres for enhanced photocatalytic degradation of acetaminophen in water. Effects of perioperative intravenous low dose of ketamine on postoperative analgesia in children. Esmolol versus ketamine-remifentanil combination for early postoperative analgesia after laparoscopic cholecystectomy: a randomized controlled trial.

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Acetaminophen (paracetamol) oral absorption and clinical influences. In-vitro characterization of buccal iontophoresis: the case of sumatriptan succinate. Investigation of in vivo antioxidant activity of Euphorbia helioscopia latex and leaves methanol extract: a target against oxidative stress induced toxicity. Single on-chip gold nanowires for electrochemical biosensing of glucose. Frequent use of paracetamol and risk of allergic disease among women in an Ethiopian population. Metoclopramide as a painkiller for intense migraine headache in emergency departments. New potential humic acid stationary phase toward drug components: Development of a chemometric-assisted RP-HPLC method for the determination of paracetamol and caffeine in tablet formulations.

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Buprenorphine, Clonidine, Dexamethasone, and Ropivacaine for Interscalene Nerve Blockade: A Prospective, Randomized, Blinded, Ropivacaine Dose-Response Study. Efficacy of Intravenous Infusion of Acetaminophen for Intrapartum Analgesia. Poisoning hospitalisations among reproductive-aged women in the USA, 1998-2006. Acute Liver Failure Due to Acetaminophen Poisoning in Patients With Prior Weight Loss Surgery: A Case Series. Mephenesin: abuse and dependence. Neuroprotective effects vary across nonsteroidal antiinflammatory drugs in a mouse model of developing excitotoxic brain injury. Hepatic mtDNA-TLR9-microRNA-223 forms a negative feedback loop to limit neutrophil over-activation and acetaminophen hepatotoxicity.

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Prenatal paracetamol exposure is associated with shorter anogenital distance in male infants. Delayed gastric emptying in diabetic rats caused by decreased expression of cystathionine gamma lyase and H2 S synthesis: in vitro and in vivo studies. Pain medications in the locker room: to dispense or not. Prenatal and infant exposure to acetaminophen and ibuprofen and the risk for wheeze and asthma in children. A validated high-performance thin layer chromatography method for estimation of lornoxicam and paracetamol in their combined tablet dosage form. In vitro validation of drug-induced phospholipidosis. Gabapentin Inhibits Protein Kinase C Epsilon Translocation in Cultured Sensory Neurons with Additive Effects When Coapplied with Paracetamol (Acetaminophen).

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The Prevalence and Determinants of Controlled Substance Discrepancies in a Level I Trauma Hospital. Identification of potential biomarkers of hepatitis B-induced acute liver failure using hepatic cells derived from human skin precursors. Time to analgesia in an emergency department in Eastern Nepal. Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening. Evaluation of cytotoxicity and DNA damage response with analysis of intracellular ATM signaling pathways. Comparison of the effects of N-acetyl cysteine and erdosteine in rats with renal injury caused by paracetamol intoxication. Crystallization of poly(ethylene oxide) with acetaminophen--a study on solubility, spherulitic growth, and morphology.

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Self-medication of regular headache: a community pharmacy-based survey in Belgium. Fragment-based discovery of bromodomain inhibitors part 1: inhibitor binding modes and implications for lead discovery. Simultaneous quantification of paracetamol, acetylsalicylic acid and papaverine with a validated HPLC method. Incidence and Management of Infusion Reactions to Infliximab in a Prospective Real-world Community Registry. Overdose of propafenone surreptitiously sold as "Percocet". Demographics of toxic exposures presenting to three public hospital emergency departments in Singapore 2001-2003. The effect of acetaminophen on the expression of BCRP in trophoblast cells impairs the placental barrier to bile acids during maternal cholestasis.

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Single-shot lamina technique of paravertebral block as an adjunct to general anesthesia for modified radical mastectomy. BLT1 signalling protects the liver against acetaminophen hepatotoxicity by preventing excessive accumulation of hepatic neutrophils. Polycystic Kidney Disease, Autosomal Recessive Treating chronic non-cancer pain in older people--more questions than answers? Age-related decrease in cerebrovascular-derived neuroprotective proteins: effect of acetaminophen. Primary Caregiver Perception of Pain Control following Pediatric Adenotonsillectomy: A Cross-Sectional Survey. Preparation and characterization of directly compactible layer-by-layer nanocoated cellulose.

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Intravenous paracetamol versus dexketoprofen in acute migraine attack in the emergency department: a randomised clinical trial. Percutaneous vertebroplasty under local anaesthesia: feasibility regarding patients' experience. Screening and quantitative determination of twelve acidic and neutral pharmaceuticals in whole blood by liquid-liquid extraction and liquid chromatography-tandem mass spectrometry. Effects of phillyrin and forsythoside A on rat cytochrome P450 activities in vivo and in vitro. Blood gene expression profiling of an early acetaminophen response. Corrigendum: Effect of Acetaminophen Ingestion on Thermoregulation of Normothermic, Non-febrile Humans. Multimodal analgesia for hip arthroplasty.

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