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Levaquin belongs to the class of medicines known as quinolone antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

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Similar Products:
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Also known as:  Levofloxacin.


Generic Levaquin is a perfect remedy. Its target is to struggle against infections such as chronic bronchitis, and sinus, urinary tract, pneumonia, kidney, and skin infections. Generic Levaquin acts by eliminating bacteria. It is fluoroquinolone.

Generic name of Generic Levaquin is Levofloxacin.

Levaquin is also known as Levofloxacin, Levotab, Levotas, Tavanic, Gatigol, Lebact, Terlev, Cravit, Levox, Levores.

Brand name of Generic Levaquin is Levaquin.


The usual dose of Levaquin Tablets or Oral Solution is 250 mg, 500 mg, or 750 mg administered orally every 24 hours, as indicated by infection and described in Table 1. The usual dose of Levaquin Injection is 250 mg or 500 mg administered by slow infusion over 60 minutes every 24 hours or 750 mg administered by slow infusion over 90 minutes every 24 hours.


Overdose of the drug should be strictly avoided and if anyone has accidentally taken the overdose of the drug, then the victim should be provided with emergency medical help. Overdose victim can also consult to their local poison helpline. Some of the overdose symptoms include loss of coordination, drooping eyelids, weakness, decreased activity, trouble breathing, sweating, tremors, or seizure.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep in a tightly closed container. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

Cluster of Stenotrophomonas maltophilia endocarditis after prosthetic valve replacement. Clinical impact of fluoroquinolone-resistant Escherichia coli in the fecal flora of hematological patients with neutropenia and levofloxacin prophylaxis. Effectiveness of fosfomycin combined with other antimicrobial agents against multidrug-resistant Pseudomonas aeruginosa isolates using the efficacy time index assay. Effects of awakening and the use of topical dexamethasone and levofloxacin on the cytokine levels in tears following corneal transplantation. Levofloxacin-azithromycin combined triple therapy for Helicobacter pylori eradication. Buy levaquin. Levofloxacin treatment failure in Haemophilus influenzae pneumonia.


Risk of tendinitis and tendon rupture is increased. This risk is further increased in older patients usually over 60 years of age, in patients taking corticosteroids, and in patients with kidney, heart and lung transplants. Discontinue if pain or inflammation in a tendon occurs.

Anaphylactic reactions and allergic skin reactions, serious, occasionally fatal, may occur after first dose.

Hematologic (including agranulocytosis, thrombocytopenia), and renal toxicities may occur after multiple doses.

Hepatotoxicity: Severe, and sometimes fatal, hepatoxicity has been reported. Discontinue immediately if signs and symptoms of hepatitis occur.

Central nervous system effects, including convulsions, anxiety, confusion, depression, and insomnia may occur after the first dose. Use with caution in patients with known or suspected disorders that may predispose them to seizures or lower the seizure threshold.

Clostridium difficile-associated colitis: evaluate if diarrhea occurs.

Peripheral neuropathy: discontinue if symptoms occur in order to prevent irreversibility.

Prolongation of the QT interval and isolated cases of torsade de pointes have been reported. Avoid use in patients with known prolongation, those with hypokalemia, and with other drugs that prolong the QT interval.

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A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection. Effect of High-Dose Antimicrobials on Biofilm Growth of Achromobacter Species Isolated from Cystic Fibrosis Patients. Partial bilateral rupture of the Achilles tendon associated to levofloxacin. Efficacy of a 7-day course of furazolidone, levofloxacin, and lansoprazole after failed Helicobacter pylori eradication. Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756. Occurrence and elimination of antibiotics at four sewage treatment plants in Japan and their effects on bacterial ammonia oxidation. Fluoroquinolones in the management of community-acquired pneumonia.

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The dipstick test in the diagnosis of UTI and the effect of pretreatment catheter exchange in catheter-associated UTI. Identification of CTX-M β-lactamases among Escherichia coli from the community in New York City. Activity of levofloxacin in combination with colistin against Acinetobacter baumannii: In vitro and in a Galleria mellonella model. Traveler's diarrhea in Thailand: randomized, double-blind trial comparing single-dose and 3-day azithromycin-based regimens with a 3-day levofloxacin regimen. Fluoroquinolone concentrations in plasma, urine, and bile after oral administration in rats with renal failure: useful technique for long-term bile collection. Mechanism of fluoroquinolone resistance is an important factor in determining the antimicrobial effect of gemifloxacin against Streptococcus pneumoniae in an in vitro pharmacokinetic model. Open-label assessment of levofloxacin for the treatment of acute bacterial sinusitis in adults.

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Pharmacokinetic evaluation of oral levofloxacin in human immunodeficiency virus-infected subjects receiving concomitant antiretroviral therapy. Comparison of in-vitro activities of SCH27899 and other antibiotics against Mycoplasma pneumoniae. Outbreak of meningococcal disease in and around New Delhi, India, 2005-2006: a report from a tertiary care hospital. Levofloxacin versus beta-lactamic therapy in community acquired pneumonia that requires hospitalization. Possible case of levofloxacin-induced thrombocytopenia. Synergistic effects of dexamethasone and quinolones on human-derived tendon cells. Prevention of clogging of biliary stents by administration of levofloxacin and ursodeoxycholic acid.

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Activities of levofloxacin, ofloxacin, and ciprofloxacin, alone and in combination with amikacin, against acinetobacters as determined by checkerboard and time-kill studies. Pseudomonas Aeruginosa Infection Among Liver Transplant Recipients: A Clinical Analysis of 15 Cases. Distribution of emm type and antibiotic susceptibility of group A streptococci causing invasive and noninvasive disease. Effect of clpP and clpC deletion on persister cell number in Staphylococcus aureus. Retrospective comparison of levofloxacin and moxifloxacin on multidrug-resistant tuberculosis treatment outcomes. Pharmacodynamic evaluation of tosufloxacin against Streptococcus pneumoniae in an in vitro model simulating serum concentration. Antibacterial effect of telithromycin (HMR 3647) and comparative antibiotics against intracellular Legionella pneumophila.

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Effects of Transcutol P on the corneal permeability of drugs and evaluation of its ocular irritation of rabbit eyes. One-step solvothermal synthesis of magnetic Fe3O4-graphite composite for Fenton-like degradation of levofloxacin. Trends in antibacterial resistance among Streptococcus pneumoniae isolated in the USA: update from PROTEKT US Years 1-4. Levofloxacin based triple therapy as a second-line treatment after failure of helicobacter pylori eradication with standard triple therapy. Micellar liquid chromatographic method for the simultaneous determination of Levofloxacin and Ambroxol in combined tablets: Application to biological fluids. Increasing resistance to quinolones: A four-year prospective study of urinary tract infection pathogens. Preventive effect against post-cataract endophthalmitis: drug delivery intraocular lens versus intracameral antibiotics.

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Effect of parenteral fluoroquinolone administration on persistence of vancomycin-resistant Enterococcus faecium in the mouse gastrointestinal tract. Modified sequential therapy regimens for Helicobacter pylori eradication: a systematic review. The combination of meropenem and levofloxacin is synergistic with respect to both Pseudomonas aeruginosa kill rate and resistance suppression. Catheter-related Mycobacterium abscessus bacteremia manifested with skin nodules, pneumonia, and mediastinal lymphadenopathy. Levofloxacin prophylaxis to prevent bacterial infection in chemotherapy-induced neutropenia in acute leukemia. Clarithromycin (Biaxin) extended-release tablet: a therapeutic review. Quinolone activity against anaerobes: microbiological aspects.

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Prevalence of serotype and multidrug-resistance of Streptococcus pneumoniae respiratory tract isolates in 265 adults and 36 children in Korea, 2002-2005. In vitro development of resistance to DX-619 and other quinolones in enterococci. Eosinophilic infiltrate in a patient with severe Legionella pneumonia as a levofloxacin-related complication: a case report. A case of pulmonaly bulla infection with Mycobacterium fortuitum. Activities of ciprofloxacin, levofloxacin, ofloxacin and sparfloxacin against speciated coagulase-negative staphylococci sensitive and resistant to fluoroquinolones. Variability in Prevalence of Helicobacter pylori Strains Resistant to Clarithromycin and Levofloxacin in Southern Poland. Torsades de pointes associated with fluoroquinolones: importance of concomitant risk factors.

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Characterization of fluoroquinolone and carbapenem susceptibilities in clinical isolates of levofloxacin-resistant Pseudomonas aeruginosa. A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity. In vitro activity of clinafloxacin in comparison with other quinolones against Stenotrophomonas maltophilia clinical isolates in the presence and absence of reserpine. Incidence of allergic reactions associated with antibacterial use in a large, managed care organisation. Acute hepatitis associated with the use of levofloxacin. Are fluoroquinolone-susceptible isolates of Streptococcus pneumoniae really susceptible? A comparison of resistance mechanisms in Canadian isolates from 1997 and 2003. Levofloxacin prophylaxis to prevent bacterial infection in chemotherapy-induced neutropenia in acute leukemia.

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A controlled trial of levofloxacin and lomefloxacin in the treatment of complicated urinary tract infection. In vivo antianaerobe activity of DS-8587, a new fluoroquinolone, against Fusobacterium necrophorum in a mouse model. Modified sequential therapy regimens for Helicobacter pylori eradication: a systematic review. What causes decreased erythromycin resistance in Streptococcus pyogenes? Dynamics of four clones in a southern European region from 2005 to 2012. Intrapulmonary pharmacokinetics and pharmacodynamics of high-dose levofloxacin in healthy volunteer subjects. Correlation between variable-number tandem-repeat-based genotypes and drug susceptibility in Mycobacterium avium isolates. Multicentric study in five African countries of antibiotic susceptibility for three main pathogens: Streptococcus pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa.

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Pharmacodynamic evaluation of commonly prescribed oral antibiotics against respiratory bacterial pathogens. In vitro activity of moxifloxacin against recent community-acquired respiratory tract pathogens isolated in France: a national survey. Interaction of the new ketolide ABT-773 (cethromycin) with human polymorphonuclear neutrophils and the phagocytic cell line PLB-985 in vitro. Antimicrobial susceptibility and clinical sources of Dolosigranulum pigrum cultures. Prediction of the pharmacokinetics and tissue distribution of levofloxacin in humans based on an extrapolated PBPK model. Comparison of gatifloxacin and levofloxacin administered at various dosing regimens to hospitalised patients with community-acquired pneumonia: pharmacodynamic target attainment study using North American surveillance data for Streptococcus pneumoniae. Evaluation of a Legionella outbreak emerged in a recently opening hotel.

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Fluoroquinolone resistance in clinical isolates of Klebsiella oxytoca. Aquatic persistence of eight pharmaceuticals in a microcosm study. Overview of anti-tuberculosis (TB) drugs and their resistance mechanisms. A multi-center, controlled, randomized, open-label clinical study of levofloxacin for preventing infection during the perioperative period of ultrasound-guided transrectal prostate biopsy. Comparative in vitro activities of three new quinolones and azithromycin against aerobic pathogens causing respiratory tract and abdominal wound infections. Acyl glucuronidation of fluoroquinolone antibiotics by the UDP-glucuronosyltransferase 1A subfamily in human liver microsomes. A liquid chromatography-tandem mass spectrometry assay for the determination of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, in human plasma and urine and its application to a single-dose pharmacokinetic study in healthy Chinese volunteers.

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