Also known as: Cefadroxil.
Duricef is a prescription medication used to treat infections of the urinary tract, skin, and
throat. Duricef belongs to a group of drugs called cephalosporin antibiotics. These work to kill
bacteria. This medication comes as an oral (by mouth) tablet, capsule, and liquid (suspension). It is
usually taken 1 to 2 times a day, with or without food. If Duricef causes an upset stomach, take
Duricef with food or milk. Common side effects of Duricef include nausea, vomiting, and diarrhea.
For urinary tract infections, the recommended daily dosage for children is 30 mg/kg/day in divided
doses every 12 hours. For pharyngitis, tonsillitis, and impetigo, the recommended daily dosage for
children is 30 mg/kg/day in a single dose or in equally divided doses every 12 hours. For other skin and
skin structure infections, the recommended daily dosage is 30 mg/kg/day in equally divided doses every
12 hours. In the treatment of beta-hemolytic streptococcal infections, a therapeutic dosage of Duricef
should be administered for at least 10 days.
In patients with renal impairment, the dosage of cefadroxil monohydrate should be adjusted according
to creatinine clearance rates to prevent drug accumulation. The following schedule is suggested. In
adults, the initial dose is 1000 mg of Duricef and the maintenance dose (based on the creatinine
clearance rate [mL/min/1.73 M2]) is 500 mg at the time intervals listed below.
Patients with creatinine clearance rates over 50 mL/min may be treated as if they were patients having
normal renal function.
If the patient misses a dose, the dose should be taken as soon as it is remembered. Doses thereafter
should then be evenly spaced with approximately 4-6 hours between doses, depending on the prescription
dosing. Patients should not make up a missed dose by doubling up on their medication. Taking double
doses will not speed recovery time, either. Taking doses close together or self administering a double
dose is likely to cause an overdose which may lead to other health complications. An overdose may cause
nausea, vomiting, diarrhea, dehydration, and abdominal cramps and requires immediate medical assessment.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw the medicine away after the expiration date. Keep out of the reach of children.
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