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Generic Cymbalta is an effective medication with highly developed components which is taken in treatment of serious depression and all symptoms connected with depression. Generic Cymbalta is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors (SSNRIs). Generic Cymbalta affects chemicals in the brain that may become unbalanced and cause depression.

Other names for this medication:
Ariclaim, Delok, Deloxi, Duloxetin, Duloxetina, Duloxetinum, Duxetin, Duzela, Xeristar, Yentreve

Similar Products:
Lexapro, Elavil, Celexa, Paxil


Also known as:  Duloxetine.


Generic Cymbalta is developed by medical scientists to treat major depressive disorder and general anxiety disorder. It is an antidepressant in a group of drugs called selective serotonin and norepinephrine reuptake inhibitors. Generic Cymbalta affects chemicals in the brain that may become unbalanced and cause depression.

Generic Cymbalta is also used to treat a chronic pain disorder called fibromyalgia, treat pain caused by nerve damage in people with diabetes (diabetic neuropathy) and to treat chronic musculoskeletal pain, including discomfort from osteoarthritis and chronic lower back pain.


Take Generic Cymbalta with a full glass of water with or without food.

It is recommended to take Generic Cymbalta at the same time each day.

Do not crush, chew, break, or open a delayed-release capsule. Swallow the tablet whole.

If you want to achieve most effective results do not stop using Generic Cymbalta suddenly.


If you overdose Generic Cymbalta and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

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Duloxetine 60 mg once daily dosing versus placebo in the acute treatment of major depression. Switching to duloxetine from selective serotonin reuptake inhibitor antidepressants: a multicenter trial comparing 2 switching techniques. Variation in catechol-O-methyltransferase is associated with duloxetine response in a clinical trial for major depressive disorder. A validated UV spectrophotometric method for determination of duloxetine hydrochloride. Long-term cost-effectiveness of initiating treatment for painful diabetic neuropathy with pregabalin, duloxetine, gabapentin, or desipramine. Buy cymbalta. Stress urinary incontinence in women.


Do not take Generic Cymbalta if you are allergic to Generic Cymbalta components.

Do not take Generic Cymbalta if you're pregnant or you plan to have a baby, or you are a nursing mother. This medication can cause birth defects. Tell your doctor right away if you become pregnant during treatment.

Be very careful with Generic Cymbalta if you're pregnant or you plan to have a baby. Do not take Generic Cymbalta if you are breast-feeding.

Do not take Generic Cymbalta together with thioridazine (Mellaril), or an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate). A dangerous drug interaction could occur, leading to serious side effects. You must wait at least 14 days after stopping an MAO inhibitor before you can take Generic Cymbalta. After you stop taking Generic Cymbalta, you must wait at least 5 days before you start taking an MAOI.

Generic Cymbalta can be not safety for children and people younger than 18 years old.

Do not take Generic Cymbalta if you have any of these conditions:liver or kidney disease, seizures or epilepsy, a bleeding or blood clotting disorder, glaucoma, bipolar disorder (manic depression), a history of drug abuse or suicidal thoughts.Be careful if you drive or do anything that requires you to be alert. Generic Cymbalta may impair your thinking or reactions.

Avoid alcohol.

It can be dangerous to stop Generic Cymbalta using suddenly.

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Switching from serotonin reuptake inhibitors to duloxetine in patients with resistant obsessive compulsive disorder: a case series. A pragmatic 12-week, randomized trial of duloxetine versus generic selective serotonin-reuptake inhibitors in the treatment of adult outpatients in a moderate-to-severe depressive episode. Gateways to clinical trials. Duloxetine for treating painful neuropathy or chronic pain. Dual acting reuptake inhibitors in the treatment of depression and pain. Duloxetine in obese binge eater outpatients: preliminary results from a 12-week open trial.

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Pharmacological validation of a model of cystitis pain in the mouse. A randomized, double-blind, placebo-controlled trial of duloxetine for the treatment of pain in patients with multiple sclerosis. Dry Eye Related to Commonly Used New Antidepressants. Hepatic effects of duloxetine-II: spontaneous reports and epidemiology of hepatic events. Duloxetine in patients with central neuropathic pain caused by spinal cord injury or stroke: a randomized, double-blind, placebo-controlled trial. Colleague interactions and new drug prescribing behavior: the case of the initial prescription of antidepressants in Taiwanese medical centers.

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Duloxetine for the treatment of generalized social anxiety disorder: a preliminary randomized trial of increased dose to optimize response. Usefulness of duloxetine for Paclitaxel-induced peripheral neuropathy treatment in gynecological cancer patients. Development and validation of a liquid chromatography-tandem mass spectrometry assay for hair analysis of atomoxetine and its metabolites: Application in clinical practice. Escitalopram and duloxetine in major depressive disorder: a pharmacoeconomic comparison using UK cost data. Pharmacological and clinical profile of newer antidepressants: implications for the treatment of elderly patients. Duloxetine treatment and glycemic controls in patients with diagnoses other than diabetic peripheral neuropathic pain: a meta-analysis.

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Duloxetine improves oxaliplatin-induced neuropathy in patients with colorectal cancer: an open-label pilot study. Antidepressants Are Effective in Decreasing Neuropathic Pain After SCI: A Meta-Analysis. Highly enantioselective Friedel-Crafts reaction of thiophenes with glyoxylates: formal synthesis of duloxetine. Duloxetine for the management of diabetic peripheral neuropathic pain: evidence-based findings from post hoc analysis of three multicenter, randomized, double-blind, placebo-controlled, parallel-group studies. Maintenance of effect of duloxetine in patients with chronic low back pain: a 41-week uncontrolled, dose-blinded study. The relationship between functional outcomes and the treatment of anxious and painful somatic symptoms in patients with generalized anxiety disorder.

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Practical management strategies for the chronic pain patient. Duloxetine in the prevention of relapse of major depressive disorder: double-blind placebo-controlled study. Benefits and harms in clinical trials of duloxetine for treatment of major depressive disorder: comparison of clinical study reports, trial registries, and publications. Do predictive parameters exist for therapy with duloxetine in women with stress urinary incontinence? Long-term tolerability and effectiveness of duloxetine in the treatment of major depressive disorder. Assessing carrageenan-induced locomotor activity impairment in rats: comparison with evoked endpoint of acute inflammatory pain.

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A 9-week randomized trial comparing a chronotherapeutic intervention (wake and light therapy) to exercise in major depressive disorder patients treated with duloxetine. Pharmacological validation of early and late phase of rat mono-iodoacetate model using the Tekscan system. Update on duloxetine for the management of stress urinary incontinence. Is there a place for the physician's hopelesness in the treatment of depression? Electroretinographic assessment in major depressed patients receiving duloxetine: might differences between responders and non-responders indicate a differential biological background? Duloxetine in the treatment of urinary incontinence in women.

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Syndrome of inappropriate antidiuretic hormone secretion: a story of duloxetine-induced hyponatraemia. Early reduction in painful physical symptoms is associated with improvements in long-term depression outcomes in patients treated with duloxetine. Tolerability and efficacy of duloxetine in a nontrial situation. Dosing patterns for duloxetine and predictors of high-dose prescriptions in patients with major depressive disorder: analysis from a United States third-party payer perspective. Duloxetine in the treatment of chronic migraine. HPLC analysis of the novel antidepressant duloxetine in human plasma after an original solid-phase extraction procedure.

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Subchronic duloxetine administration alters the extended amygdala circuitry in healthy individuals. Electrophysiological characterization of the effect of long-term duloxetine administration on the rat serotonergic and noradrenergic systems. The influence of smoking on the serum level of duloxetine. Serotonin-Norepinephrine Reuptake Inhibitors and the Risk of AKI: A Cohort Study of Eight Administrative Databases and Meta-Analysis. Human P-glycoprotein differentially affects antidepressant drug transport: relevance to blood-brain barrier permeability. Development and validation of a liquid chromatography-tandem mass spectrometric method for the determination of the major metabolites of duloxetine in human plasma.

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Duloxetine compared with fluoxetine and venlafaxine: use of meta-regression analysis for indirect comparisons. Investigation on the enantioseparation of duloxetine by capillary electrophoresis, NMR, and mass spectrometry. Antihyperalgesic effect of duloxetine and amitriptyline in rats after peripheral nerve injury: Influence of descending noradrenergic plasticity. Electrophysiological characterization of the effect of long-term duloxetine administration on the rat serotonergic and noradrenergic systems. Fibromyalgia: mechanisms, current treatment and animal models. Conservative management of postoperative urinary incontinence in men.

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The relationship between average daily dose, medication adherence, and health-care costs among diabetic peripheral neuropathic pain patients initiated on duloxetine therapy. Metabolism of the newest antidepressants: comparisons with related predecessors. Duloxetine versus venlafaxine in the treatment of unipolar and bipolar depression. Prior stress exposure increases pain behaviors in a rat model of full thickness thermal injury. Relationship between serotonin transporter occupancies and analgesic effects of AS1069562, the (+)-isomer of indeloxazine, and duloxetine in reserpine-induced myalgia rats. Onset of action for duloxetine 60 mg once daily: double-blind, placebo-controlled studies.

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Duloxetine in the treatment of depression: a double-blind placebo-controlled comparison with paroxetine. Duloxetine attenuated morphine withdrawal syndrome in the rat. Antidepressants and their onset of action: a major clinical, methodological and pronostical issue. Safety and efficacy of duloxetine in the treatment of diabetic peripheral neuropathic pain in older patients. Genetic variation in IL-1β, IL-2, IL-6, TSPO and BDNF and response to duloxetine or placebo treatment in major depressive disorder. Prescribing patterns and safety monitoring of duloxetine using the Danish Register of Medicinal Product Statistics as a source.

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