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Buy Aldactone (Spironolactone)
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Buy Aldactone

Generic Aldactone is an effective medication which helps to fight with hyperaldosteronism, hypokalemia, edema, ascites, hirsutism, alopecia (baldness), acne. It can be also used together with other medicines to treat myasthenia gravis, precocious puberty, high blood pressure. Generic Aldactone acts by controlling the level of water and salt and by decreasing the potassium loss from your body.

Other names for this medication:
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Similar Products:
Dyazine, Lasix, Aldactone, Microzide, Demadex, Osmitrol

 

Also known as:  Spironolactone.

Description

Generic Aldactone is a perfect remedy, which helps to fight with hyperaldosteronism, hypokalemia, edema, ascites, hirsutism, alopecia (baldness), acne. It can also be used together with other medicines to treat myasthenia gravis, precocious puberty, high blood pressure.

Generic Aldactone acts by controlling the level of water and salt and by decreasing the potassium loss from your body.

Aldactone is also known as Spironolactone, Spirotone, Spiractin, Osyrol, Spiroctan, Spirolon, Verospiron.

It is aldosterone receptor antagonists.

Generic name of Generic Aldactone is Spironolactone.

Brand names of Generic Aldactone are Aldactone, Spiractin, Spirotone, Spironol, Berlactone, Novo-Spiroton.

Dosage

You can feel the effects of Generic Aldactone after 2 weeks of treatment. It depends on the health state and other factors of the patient.

Take Generic Aldactone tablets orally with water, at the same time every day.

Do not crush or chew it.

Take Generic Aldactone once (in the morning) or twice a day.

If you want to achieve most effective results do not stop taking Generic Aldactone suddenly.

Overdose

If you overdose Generic Aldactone and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Aldactone overdosage: diarrhea, vomiting, nausea, red skin rash, loss of energy, slow heartbeat, weakness in legs, feeling drowsy, confusion.

Storage

Store below 25 degrees C (77 degrees F). Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effects

New potentialities in the treatment of idiopathic hyperaldosteronism. Hypokalemia: causes, consequences and correction. Spironolactone diminishes spontaneous ventricular premature beats by reducing HCN4 protein expression in rats with myocardial infarction. Chemopreventive effect of five drugs on renal interstitial fibrosis induced by an aristolochic acid-containing Chinese herb in rats. Buy aldactone. Spironolactone might be a desirable immunologic and hormonal intervention in autism spectrum disorders.

Contraindications

Do not take Generic Aldactone if you are allergic to Generic Aldactone components.

Do not take Generic Aldactone if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Aldactone can harm your baby.

Do not take Generic Aldactone if you are taking potassium-sparing diuretics (such as Aldactazide, amiloride (Moduretic, Midamor)), triamterene (such as Maxzide, Dyazide, Dyrenium)).

Be careful using Generic Aldactone if you take inhibitors (enalapril (such as Vasotec), fosinopril (such as Monopril), captopril (such as Capoten), benazepril (such as Lotensin), lisinopril (such as Zestril, Prinivil), quinapril (such as Accupril), moexipril (such as Univasc), ramipril (such as Altace), trandolapril (such as Mavik)); oral steroids (dexamethasone (such as Decadron, Dexone), prednisone (such as Deltasone), methylprednisolone (such as Medrol)); aspirin and other nonsteroidal anti-inflammatory medicines (naproxen (such as Aleve, Naprosyn), ibuprofen (such as Advil, Motrin), indomethacin (such as Indocin)); diuretics; barbiturates, phenobarbital; digoxin (such as Digitek, Lanoxicaps, Lanoxin)); high blood pressure medicines, lithium (such as Lithobid, Eskalith); perindopril (such as Aceon).It can be dangerous to use Aldactone if you suffer from or have a history of liver disease, kidney disease, potassium high levels in your blood, problems with urination.

Be careful with this drug if you are going to have a surgery.

Avoid food with high level of salt.

Avoid dehydration.

Avoid medicines which cause lightheadedness.

You should be careful when you are driving or operating machinery.

Do not stop taking Generic Aldactone suddenly.

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Effects of additive therapy with spironolactone on albuminuria in diabetes mellitus: A pilot randomized clinical trial. Effect of RAAS antagonist on the expression of gap junction cx43 in myocardium of spontaneously hypertensive rat. Eplerenone mimics features of the alternative activation in macrophages obtained from patients with heart failure and healthy volunteers. Independence of salt intake induced by calcium deprivation from the renin-angiotensin-aldosterone system. Bidirectional (positive/negative) interference of spironolactone, canrenone, and potassium canrenoate on serum digoxin measurement: elimination of interference by measuring free digoxin or using a chemiluminescent assay for digoxin. Spiroboronate Si-rhodamine as a near-infrared probe for imaging lysosomes based on the reversible ring-opening process. The glucocorticoid receptor antagonist mifepristone reduces ethanol intake in rats under limited access conditions. Aldosterone potentiates angiotensin II-induced signaling in vascular smooth muscle cells.

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Efficacy and safety of the selective aldosterone blocker eplerenone in Japanese patients with hypertension: a randomized, double-blind, placebo-controlled, dose-ranging study. The importance of apoptotic activity and plasma NT-proBNP levels in patients with acute exacerbation of decompensated heart failure and their relation to different drugs and comorbidities. Gender differences in urinary kallikrein excretion in man: variation throughout the menstrual cycle. Clinical effects of combined treatment by optimal dose of furosemide and spironolactone on diastolic heart failure in elderly patients. Differential interaction of clinical characteristics with key functional parameters in heart failure with preserved ejection fraction--results of the Aldo-DHF trial. Cellular mechanisms of digoxin transport and toxic interactions in the kidney. Role of the combination spironolactone-norgestimate-estrogen in Hirsute women with polycystic ovary syndrome. Effects of antihypertensive drugs on hepatic heme biosynthesis, and evaluation of ferrochelatase inhibitors to simplify testing of drugs for heme pathway induction.

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Comparison of the efficiency of anti-androgenic regimens consisting of spironolactone, Diane 35, and cyproterone acetate in hirsutism. Potentiation by aldosterone of vasopressin-induced calcium kinetics in vascular smooth muscle cells. Role of osteopontin in cardiac fibrosis and remodeling in angiotensin II-induced cardiac hypertrophy. Aldosterone sensitizes connecting tubule glomerular feedback via the aldosterone receptor GPR30. Central mineralocorticoid receptors and the role of angiotensin II and glutamate in the paraventricular nucleus of rats with angiotensin II-induced hypertension. Involvement of brain mineralocorticoid receptor in salt-enhanced hypertension in spontaneously hypertensive rats. The conversion of oridonin to spirolactone-type or enmein-type diterpenoid: synthesis and biological evaluation of ent-6,7-seco-oridonin derivatives as novel potential anticancer agents. Changes in the electrolyte content of leucocytes at different clinical stages of cirrhosis.

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Angiotensin-converting enzyme inhibitors in heart failure: physicians' prescribing behavior. Plasma aldosterone level in a female case of pseudohyperaldosteronism (Liddle's syndrome). Corticosterone suppresses the proliferation of RAW264.7 macrophage cells via glucocorticoid, but not mineralocorticoid, receptor. Both mineralocorticoid and glucocorticoid receptors regulate emotional memory in mice. Paroxysmal atrial fibrillation with asystole and syncope: report of a case of sinus node dysfunction with hypokalemia and hypertension. Protective effects of selective mineralocorticoid receptor antagonist against aortic aneurysm progression in a novel murine model. Effectiveness of nutritional support for the liver-cell deficiency in the liver cirrhosis. Drug therapy in chronic heart failure.

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Safety of spironolactone use in ambulatory heart failure patients. Corticosteroid and progesterone transactivation of mineralocorticoid receptors from Amur sturgeon and tropical gar. Beneficial effects of spironolactone on glomerular injury in streptozotocin-induced diabetic rats. Positive effect of eplerenone treatment on endothelial progenitor cells in patients with chronic heart failure. Changing views on the place of loop and thiazide diuretics in the treatment of chronic heart failure. Part II. Influence on outcomes and clinical application. Primary aldosteronism with right-dominant heart failure. The effect of diuretics on extrarenal potassium tolerance. Discordant genotype-phenotype correlation in familial hyperaldosteronism type III with KCNJ5 gene mutation: a patient report and review of the literature.

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Normal pregnancy outcome following inadvertent exposure to rosiglitazone, gliclazide, and atorvastatin in a diabetic and hypertensive woman. Drug and chemical-induced metabolic acidosis. Hormonal regulation of cardiac growth: hypothesis with regard to the adrenal cardiotropic steroid. Mineralocorticoid receptor blockade improves vasomotor dysfunction and vascular oxidative stress early after myocardial infarction. Glucocorticoid mediated regulation of inflammation in human monocytes is associated with depressive mood and obesity. Spironolactone in combination with cilazapril ameliorates proteinuria and renal interstitial fibrosis in rats with anti-Thy-1 irreversible nephritis. Safety and efficacy of eplerenone in patients at high risk for hyperkalemia and/or worsening renal function: analyses of the EMPHASIS-HF study subgroups (Eplerenone in Mild Patients Hospitalization And SurvIval Study in Heart Failure). Differential regulation of Na+-K+-ATPase gene expression by corticosteriods in vascular smooth muscle cells.

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Albuminuria is associated with an increased prostasin in urine while aldosterone has no direct effect on urine and kidney tissue abundance of prostasin. Mineralocorticoid receptor blocker eplerenone reduces pain behaviors in vivo and decreases excitability in small-diameter sensory neurons from local inflamed dorsal root ganglia in vitro. Beneficial role of spironolactone, telmisartan and their combination on isoproterenol-induced cardiac hypertrophy. Refractory ascites and dilutional hyponatremia: current management and new aquaretics. Conception and pharmacodynamic profile of drospirenone. Plasma renin activity in essential hypertension: different short- und long-term effects of diuretics (author's transl). Pre-operative evaluation of the prognosis of hypertension in primary aldosteronism owing to adenoma. Aldosterone antagonists: a new treatment option for patients with post-myocardial infarction heart failure.

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